I am too lazy to look up the calories in your "supplements", but
then you have been too lazy to list them. They are not exempt - they go
into your calorie counting. You do count calories, right? Let's not be
lazy about it 
The general recipe for weight loss whilst retaining muscle mass (and in some cases even increasing it)
1) be in a calorie deficit, you should aim to lose up to 1% of your body weight per week (say 3lb a week at 300lb)
2) strength training to at least maintain your muscles
3) adequate protein intake aiming for 0.5g-1g of body weight (translates to 150g-300g for you). This is combined from both your food and your supplements (which are food, see point about calories above)
I strongly suggest calorie awareness - tracking your calories on a calorie-counting website, phone app or stand-alone computer program. (or a spreadsheet or you can do it with pen and paper)
One exception to that "rule" would be to eat super-healthy as in the graphic below, but bear in mind you will have to modify it by "supplementing" with extra lean protein and/or Whey protein to reach protein goals mentioned above

http://www.caloriesperhour.com/forums/forum8/15000.html

The general recipe for weight loss whilst retaining muscle mass (and in some cases even increasing it)
1) be in a calorie deficit, you should aim to lose up to 1% of your body weight per week (say 3lb a week at 300lb)
2) strength training to at least maintain your muscles
3) adequate protein intake aiming for 0.5g-1g of body weight (translates to 150g-300g for you). This is combined from both your food and your supplements (which are food, see point about calories above)
I strongly suggest calorie awareness - tracking your calories on a calorie-counting website, phone app or stand-alone computer program. (or a spreadsheet or you can do it with pen and paper)
One exception to that "rule" would be to eat super-healthy as in the graphic below, but bear in mind you will have to modify it by "supplementing" with extra lean protein and/or Whey protein to reach protein goals mentioned above

http://www.caloriesperhour.com/forums/forum8/15000.html
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